Model of attachment of <i>S. epidermidis</i> to an implanted DL.
figure
posted on 2009-05-01, 11:37 authored by Carlos Arrecubieta, Faustino A. Toba, Manuel von Bayern, Hirokazu Akashi, Mario C. Deng, Yoshifumi Naka, Franklin D. Lowy<p>A model illustrating the potential role of SdrF in <i>S. epidermidis</i> colonization and infection of a transcutaneous driveline (DL). SdrF mediates the initial attachment of <i>S. epidermidis</i> found colonizing the skin to Dacron fibers. Bacteria cross the transcutaneous site (TC) and adhere via the SdrF B domain to collagen fibers (Cn) deposited on the internal DL surface, leading to subsequent biofilm (BF) formation, colonization, and potential infection.</p>
