Minimal vascular pulmonary remodeling after MCT.
Figures are generally photos, graphs and static images that would be represented in traditional pdf publications.
A. Representative images 400x indicating only mild thickening of pulmonary arterioles from WT and COX-2 KD mice after MCT compared to saline. Lower panels are representative of WT and COX-2 KD MCT-treated mice that required euthanasia. Sections were stained with H&E. Lungs from 38 mice were evaluated microscopically with 2 lung sections/mouse, as follows: WT/saline, n = 6; COX-2 KD saline, n = 6; WT/MCT, n = 14; COX-2 KD/MCT, n = 12. B. Representative photomicrographs at 200x (a, c) of lung sections from a COX-2 KD MCT-treated mouse showing pulmonary mild perivascular edema with neutrophil infiltration in small arterioles. Boxed areas from a and c are shown at 400x in b and d.