Microstructure appearance of the NGF–CMSs, CCH, and NGF–CMSs/CCH.
Scanning electron microscopy images of the NGF–CMSs (A and B) show relative rough surface and spherical shape without hollows or deformations. Scanning electron microscopy images of the CCH scaffold in a transverse section (C) show that the microchannels were arranged in a honeycomb-like pattern. The longitudinal section of the CCH (D) shows the longitudinally oriented microchannels. Scanning electron microscopy images of the NGF–CMSs/CCH in a transverse section (E) show slightly different morphologies with pores, which were less regular and smaller than that of the CCH scaffold. The longitudinal section of the NGF–CMSs/CCH shows that the NGF–CMSs were evenly distributed throughout the longitudinally oriented microchannels which did not influence the microstructures of the scaffolds.