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Microarray analysis of miR-7-downregulated genes in HN5 and FaDu cells.

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posted on 24.10.2012, 01:23 authored by Felicity C. Kalinowski, Keith M. Giles, Patrick A. Candy, Alishum Ali, Clarissa Ganda, Michael R. Epis, Rebecca J. Webster, Peter J. Leedman

(A) Volcano plots representing array probes between HN5 (left) and FaDu (right) cells 24 h after transfection with miR-7 or miR-NC precursor molecules. Assigning a cut off of ±1.5-fold change (miR-7 vs miR-NC) and p<0.05, significantly downregulated probes are in green and significantly upregulated probes are in red. (B) Cluster analysis of miR-7-downregulated genes in HN5 and FaDu cells, where green and red shading corresponds to downregulated and upregulated genes, respectively. (C) Venn diagram of miR-7-downregulated genes in HN5 and FaDu cells. (D) Scatter plot of miR-7-downregulated genes common to HN5 and FaDu cells (R2 = 0.435, p<0.001).

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