Methylation pattern of 4 single copy genes in WT ESCs, embryonic liver, and MEFs and in Dnmt KO ESCs.
figureposted on 28.06.2012, 02:01 by Julia Arand, David Spieler, Tommy Karius, Miguel R. Branco, Daniela Meilinger, Alexander Meissner, Thomas Jenuwein, Guoliang Xu, Heinrich Leonhardt, Verena Wolf, Jörn Walter
For detailed description see legend Figure 1. In Dnmt1 KO all analyzed regions show a hypomethylated state. In Dnmt3a/3b KO sequence specific differences become obvious.