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Major histopathological subtypes of canine colorectal tumors investigated.

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posted on 10.12.2012 by Lydia Youmans, Cynthia Taylor, Edwin Shin, Adrienne Harrell, Angela E. Ellis, Bernard Séguin, Xinglai Ji, Shaying Zhao

Shown from top to bottom are H&E staining images for normal colon (mucosa, submucosa, and muscle layers as indicated), colorectal adenoma, and colorectal adenocarcinoma. In the adenoma (middle), there is preservation of a distinct basement membrane (arrows). In the adenocarcinoma (bottom), a section of the basement membrane (small arrows) has been disrupted and penetrated through by neoplastic cells invading the submucosa (large arrow).

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