Macrophage ER stress is increased in vitamin D deficiency.
figure
posted on 2013-01-22, 01:24 authored by Sherry Weng, Jennifer E. Sprague, Jisu Oh, Amy E. Riek, Kathleen Chin, Miguel Garcia, Carlos Bernal-MizrachiApoE−/− mice were assessed after vitamin D-sufficient (black) or –deficient (white) HFD. (A) Western blot and (B) quantification of ER stress protein expression (n = 4 per group) in unstimulated peritoneal macrophages. (C) Triple immunofluorescent staining of the aortic root of vitamin D –sufficient (top) or –deficient (bottom) for DAPI (blue), CHOP (red), and MOMA (green). Data expressed as mean ± SEM. *p<0.05, **p<0.01, ***p≤0.0001.
