Figure_9.tif (1.38 MB)

Location of potential miRNA target sites on the 3′ UTR sequences of oSCF (+/−)

Download (0 kB)
figure
posted on 15.06.2012 by Siva Arumugam Saravanaperumal, Dario Pediconi, Carlo Renieri, Antonietta La Terza

. Vertical black bars on the schematic diagram represent miRNA target sites on the 3′ UTR region. Open and dotted boxes represent potential miRNA target sites and sequence conservation, through evolution in sheep, goat, cow, dog, horse and pig. (a) The predicted potential binding site of miR-27a,b on the 3′ UTR of ovine s-SCF (+) and stemloop structure (mfold) of the miR-27a,b is shown. The seed sequences (nt. 2 to nt. 8) of the miR-27a,b is shown in red, bold letters. The target nucleotides involved in pairing are shown in blue, bold on the ovine s-SCF (+). The nucleotides involved in pairing outside the seed sequence are underlined in black; (b) The predicted potential binding site of miR-669f-3p on the 3′ UTR of ovine m-SCF (−) and stemloop structure (mfold) of the mature miR-669f-3p is shown. The miR-669f-3p target sequence is located on the non-coding intron-5 closest to exon 5. The mature miR-669f-3p is shown in red, bold letters. The target nucleotides involved in pairing are shown in blue, bold on the ovine m-SCF (−).

History

Licence

Exports