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Light micrographs of an autopsied mouse that died due to cardiac rupture.

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posted on 20.02.2013, 17:00 by Mikihiko Arikawa, Yoshihiko Kakinuma, Takemi Handa, Fumiyasu Yamasaki, Takayuki Sato

(a) An infarcted mouse after the incidence of cardiac rupture. The chest cavity was filled with a large amount of clotted blood surrounding the heart. (b) The heart excised from the mouse. The ischemic area was visually identified by the pale myocardium. A white arrowhead represents the position of the coronary artery ligation. (c) An enlarged micrograph of the area shown by the small rectangle with a broken line in (b). A left ventricular perforation tends to occur at the border zone between infarcted and non-infarcted myocardium (black arrowheads). (d) The ruptured heart sectioned at a middle part of the left ventricular infarct area. The tissue was stained with hematoxylin and eosin. A black arrowhead shows the position of wall perforation occurred at left ventricular infarct border zone. RV, right ventricle; LV, left ventricle; IA, infarct area.