Levels of 8-hydroxy-2′ deoxyguanosine (8-OHdG) in the lungs after hemorrhagic shock and resuscitation (HSR).
Lungs from the HSR group rats treated with or without biliverdin (BV) were excised 3 h after resuscitation and mitochondrial 8-OHdG levels were measured. Data are presented as means ± standard deviation (n = 5 per group). Statistical analysis was performed using analysis of variance followed by Tukey–Kramer honestly significant difference test. *p<0.05 vs. vehicle/sham; †p<0.05 vs. BV/sham; #p<0.05 vs. vehicle/HSR. Vehicle/sham, vehicle-administered animals subjected to sham surgery; BV/sham, BV-administered animals subjected to sham surgery; vehicle/HSR, vehicle-administered animals subjected to HSR; BV/HSR, BV-administered animals subjected to HSR.