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Download fileLearning capacity was assessed in the Morris water maze after 4 training days.
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posted on 2014-11-19, 17:20 authored by Fabian D. Liechti, Nicolas Stüdle, Regula Theurillat, Denis Grandgirard, Wolfgang Thormann, Stephen L. LeibIn probe trials, the mean distance of the animals to the previous location of the platform was calculated. LiCl led to a significantly improved learning capacity compared to NaCl on day 5 (2way ANOVA). In post-hoc analysis, the effect of LiCl treatment was significant in infected animals (PM+) while it remained below statistical significance in mock-infected animals (PM−). (Boxes extend from the 25th to 75th percentiles and include median; +, mean; whiskers, minimum to maximum value; *p<0.05).
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attenuate neurofunctional deficitsbdnfMorris water mazeExperimental Meningitis Pneumococcal meningitisbaxChronic LiCl treatmentinfant rat modelmood stabilizer lithiumcsfpneumococcal meningitisinfectionapoptosilithiumserumhippocampal dentate gyrusHippocampal gene expressionbcltnfilattenuate brain damagemcp