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LAP2 is overexpressed in diverse digestive tract cancers.

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posted on 2013-02-20, 03:42 authored by Hyun-Jung Kim, Sun-Hwi Hwang, Myoung-Eun Han, Sungmin Baek, Hey-Eun Sim, Sik Yoon, Sun-Yong Baek, Bong-Seon Kim, Jeong-Hwan Kim, Seon-Young Kim, Sae-Ock Oh

(A) Immunohistochemical staining showed overexpression of LAP2 in diverse digestive tract cancers including pancreas, liver, stomach and bile duct cancers. Note overexpression of LAP2 in metastatic cancer cells. Scale bar, 200 µm. (B) Overexpression of LAP2β in gastric cancer tissues was examined by real-time PCR using specific primers for the β-isoform. GAPDH was used to normalize all data.