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Knock down of PRR11 inhibited cell proliferation and GC cell colony forming ability in the SGC-7901 gastric carcinoma cell line.

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posted on 07.08.2015, 04:01 by Zongchang Song, Wenying Liu, Yu Xiao, Minghui Zhang, Yan Luo 1, Weiwei Yuan, Yu Xu, Guanzhen Yu, Yide Hu

(A) Western blot analysis of PRR11 expression at 48 hours after transfection of PRR11-shRNA in SGC7901 cells; (B, C) Silencing of PRR11 inhibits cell proliferation (B) and colony forming ability in vitro (C). (D) Silencing of PRR11 inhibited tumor grow in vivo. *P<0.05, **P<0.01, **P<0.01 considered statistically significant compared with control.