Knock down of PRR11 inhibited cell proliferation and GC cell colony forming ability in the SGC-7901 gastric carcinoma cell line.
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(A) Western blot analysis of PRR11 expression at 48 hours after transfection of PRR11-shRNA in SGC7901 cells; (B, C) Silencing of PRR11 inhibits cell proliferation (B) and colony forming ability in vitro (C). (D) Silencing of PRR11 inhibited tumor grow in vivo. *P<0.05, **P<0.01, **P<0.01 considered statistically significant compared with control.