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Kinetic analysis of oxaliplatin degradation in membrane vesicle incubation buffer containing glutathione.

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posted on 01.07.2015, 04:05 by Khine Myint, Yan Li, James Paxton, Mark McKeage

Open symbols represent individual values of oxaliplatin chromatographic peak areas pooled from two independent experiments. The line represents a nonlinear one phase exponential decay regression fit (r2 = 0.964) to the data giving an oxaliplatin degradation half-life of 2.24 hours (95%CI, 2.08 to 2.43 hours).