Kaplan-Meier survival curves of female TG9 mice treated with 40 µg/kg/day of exenatide subcutaneously (divided b.i.d.) or vehicle beginning at 56 days of life and continuing until the time of death.

Panel A: Exenatide-treated mice (n = 9) versus vehicle (n = 6), p-value <0.01. Panel B: Exenatide and vehicle treated mice given ritonavir daily by intraperitoneal injection (10 mg/kg) beginning at 75 days of age and continuing until the time of death (n = 7 and 12 respectively per group).