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KIR3DL1 subgroup typing accurately predicts NK phenotypes by multi-parameter flow cytometry.
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posted on 2014-06-11, 03:04 authored by Jeanette E. Boudreau, Jean-Benoît Le Luduec, Katharine C. HsuNK cells from eight representative healthy donors were surface-stained with DX9 and Z27 antibodies. KIR3DL1 subtypes identified by the multiplex typing method have known expression characteristics and they are indicated below each of the eight flow cytometry plots shown. KIR3DL1 subtyping and NK phenotypes were consistent for all 104 individuals tested.
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cell biologyCellular typesAnimal cellsBlood cellsWhite blood cellsNK cellsImmune cellsgeneticsGenetic lociallelesGenetics of diseaseGenetic predispositionhistocompatibilityimmunologyClinical immunologyGenetics of the immune systemInfectious diseasesViral diseasesaidsHIV infectionssubgrouptypingnkphenotypesmulti-parameter
