Interferon-α restores FR901228-induced MICA/B surface expression after VSV infection.
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JE6-1 cells were treated twice with 1000 U IFN-α with a 24 hr interval. One hr after the second treatment with IFN-α, the cells were mock infected or infected with 0.01 MOI VSV10. One hr post infection the cells were treated with 20 ng/mL FR901228 (FR), where indicated. 19 hr post infection, the cells were analyzed for MICA/B surface expression by flow cytometry. The data represent one out of two experiments.