Insula.

Panel A and B - The insula was subdivided in seven-parcellated sections along the lateral fissure posterior, insular superior and inferior sulci and the insular gyrus. Panel C - We found contralateral allodynic activation in the posterior insula (lateral fissura posterior) and deactivation in the medial and anterior insula in TNP patients. Panel D – Functional (de)activations were colocalized with cortical thickness changes when comparing TNP and HC groups, with thickening in the posterior and medial insula and thinning in the anterior insula.