Figure_3.tif (143.99 kB)
Inhibiting SLIT-ROBO signalling decreases apoptosis as measured by an activated caspase-3/7 assay.
figure
posted on 2013-02-20, 11:21 authored by Rachel E. Dickinson, K. Scott Fegan, Xia Ren, Stephen G. Hillier, W. Colin DuncanA) Treatment with the ROBO1/Fc chimera reduced caspase-3/7 activity, when compared to treatment PBS/0.1% (w/v) BSA (Control) in both PEO-14 and SKOV-3 cells. B) Transfection with SLIT2 siRNA reduced caspase-3/7 activity, when compared to treatment with a scrambled siRNA control. * = P<0.05.
