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Increased cytokine response is not caused by cell wall changes of the ΔalcC strain.

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posted on 21.07.2011, 01:37 by Nora Grahl, Srisombat Puttikamonkul, Jeffrey M. Macdonald, Michael P. Gamcsik, Lisa Y. Ngo, Tobias M. Hohl, Robert A. Cramer

Secretion of MIP-2 and TNF-α by bone marrow-derived macrophages (cultured as described in Materials and Methods) incubated for 18 hours with A. fumigatus conidia (A), UV irradiated germlings (B), or UV irradiated hyphae (C). Presented are the average concentration and standard deviation in 3 wells per condition of one representative experiment. P>0.05 for all comparisons.

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