Inclusions are present in the male reproductive glandular epithelium and spleen connective tissue.
Nuclear inclusions were present in the epithelial cells of the seminal vesicles (A) and the epithelium of the coagulation gland (B) in HdhQ150/Q150 but absent from wild-type mice. A similar distribution was identified in R6/2 mice although the number of affected cells was fewer in number in both cases. Nuclear inclusions were present in connective tissue cells of the spleen capsule from HdhQ150/Q150 mice (C) with a similar distribution in R6/2. Nuclear inclusions are indicated by arrowheads. Scale bar = 20 µm.