In vivo tumor scintigraphic imaging and changes in tumor volume.
(A) Mice were subcutaneously transplanted with Hela cells in the right axilla (A3). SPECT images at 0.5 h post-injection with Na131I showed that the tumor was clearly visualized in the baculovirus-infected group (A2) but not in the PBS group (A1). (B) 131I accumulation in tumors over time. Regions of interest in the tumor were quantified and expressed as means ± SD. (C) Changes in tumor volumes after 131I treatment. Twenty-four hours after intratumoral injection with recombinant baculovirus or PBS, the mice were further injected with 37 MBq of Na131I via the tail vein. Data are presented as means ± SD. *P<0.05.