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In vivo probe signal as a function of TcapQ488 dose.

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posted on 2014-02-21, 03:19 authored by Xudong Qiu, James R. Johnson, Bradley S. Wilson, Seth T. Gammon, David Piwnica-Worms, Edward M. Barnett

Rat eyes were pretreated with 25(0.097, 0.193, 0.313, 0.387 and 0.775 nmol). All eyes were imaged at 4, 12, 24, 48 and 72 hours post-probe injection. Probe activation increased with increasing TcapQ488 doses at all but the earliest time point (4 hours post probe injection). n≥3 (5 to 8 eyes) for each time point. Data represent mean ± SEM.