In vivo murine model of DL infection measuring the ability of S. epidermidis to establish a DL infection.
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(A,B) 3.75 µg of either pre-immune (Control) IgGs or a mixture (1∶1) of anti-rASdrF and anti-rBSdrF IgGs (Anti-rA+rB) were pre-incubated with S. epidermidis 9491 cells before infection. (A) Effect of anti-SdrF IgGs on the in vivo adherence of S. epidermidis 9491 to DL. (B) Effect of anti-SdrF IgGs on the in vivo adherence of S. epidermidis 9491 to tissue surrounding the DL following implantation and infection. (C,D) Comparison of in vivo colonization between S. epidermidis strains 9491 (SdrF +) and 9 (SdrF −) to DL (C) and surrounding tissue (D). *, P<0.05.