<i>In vivo</i> murine model of DL infection measuring the ability of <i>S. epidermidis</i> to establish a DL infection.
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posted on 2009-05-01, 11:37 authored by Carlos Arrecubieta, Faustino A. Toba, Manuel von Bayern, Hirokazu Akashi, Mario C. Deng, Yoshifumi Naka, Franklin D. Lowy<p>(A,B) 3.75 µg of either pre-immune (Control) IgGs or a mixture (1∶1) of anti-rASdrF and anti-rBSdrF IgGs (Anti-rA+rB) were pre-incubated with <i>S. epidermidis</i> 9491 cells before infection. (A) Effect of anti-SdrF IgGs on the <i>in vivo</i> adherence of <i>S. epidermidis</i> 9491 to DL. (B) Effect of anti-SdrF IgGs on the <i>in vivo</i> adherence of <i>S. epidermidis</i> 9491 to tissue surrounding the DL following implantation and infection. (C,D) Comparison of <i>in vivo</i> colonization between <i>S. epidermidis</i> strains 9491 (SdrF +) and 9 (SdrF −) to DL (C) and surrounding tissue (D). *, <i>P</i><0.05.</p>
