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In vitro tissue culture assay to discover potential inhibitory activities of our sdAb clones.

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posted on 2010-01-21, 02:09 authored by Jerry O. Conway, Laura J. Sherwood, M. Thelma Collazo, John A. Garza, Andrew Hayhurst

Neuro-2A assay demonstrating the ability of some of the anti-A BoNT sdAb to inhibit the process of BoNT intoxication by reducing the intracellular cleavage of SNAP-25. + indicates toxin without sdAb and – indicates no toxin and no sdAb.