In situ hybridization of Let-7g, miR-29a and miR-30e in normal and ATC tissues.
Tissue sections from normal and tumor thyroids were incubated with a full length DIG-labeled LNA probe to detect Let-7g, miR-29a and miR-30e: 20× magnification showing a strong miRNA signal observed (in blue) in the normal thyrocytes and a weak signal observed in the tumor cells derived from thyrocytes. No signal was detected in the TAM. 4 ATC were investigated. Representative pictures of 3 of them are shown.