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Illustration of the relationship between BI- or BII-rich regions and DNA grooves.

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posted on 29.12.2010, 00:17 by Christophe Oguey, Nicolas Foloppe, Brigitte Hartmann

The BI-rich (PDB code 1EHV, left) and BII-rich (PDB code 3GGI, right) decamer X-ray structures are in the same orientations. BI and BII phosphate groups are in blue and green, respectively. Top: the lateral view shows that the minor groove (mG) is considerably enlarged in the BII-rich structure (right). Bottom: view along the major groove (MG), showing its reduced concavity in the BII-rich structure (right).

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