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Histological findings of orthotopic bone formation after treatment with various concentrations of SDF-1 with/without BMP2.

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posted on 2015-03-17, 03:25 authored by Chang-Hwan Lee, Myoung Uk Jin, Hong-Moon Jung, Jung-Tae Lee, Tae-Geon Kwon

(A) Representative histological sections 4 weeks post-surgery (trichrome staining, ×40 in the box). (B) Bone formation ratio (%) and newly formed bone area (mm2) were analyzed histomorphometrically. Concomitant BMP-2 and SDF-1 treatment did not significantly activate orthotopic bone formation compared to independent treatment with BMP-2 or SDF-1 alone (*, p < 0.05).