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Heart and muscle genes enriched in calcium signalling – muscle contraction pathway.

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posted on 2013-02-19, 18:39 authored by Clare M. Lee, Manikhandan A. V. Mudaliar, D. R. Haggart, C. Roland Wolf, Gino Miele, J. Keith Vass, Desmond J. Higham, Daniel Crowther

IPA analysis of the top 100 probe-sets from heart and muscle gene clusters (Figure 7) showed the enrichment of calcium signalling pathway. In this figure, we have highlighted the genes present in this pathway in orange. Though this pathway is generalised for skeletal muscle contraction and cardiac muscle contraction, they differ in the members of the same gene family. The heart and muscle genes present in this pathway are given in Tables 7 and 8. Pathway diagram was drawn using Path Designer function of IPA [18].