Hazard Ratios and 95% Confidence Intervals of Diabetes according to Waist Circumference in 1993–97 without (dashed line) and with (solid line) adjustment for Body Mass index in Men from the Danish Diet, Cancer and Health Study.
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Abbreviations: HR, hazard ratio. WC, waist circumference. Lines are the hazard ratios (areas the 95%-confidence intervals) derived from Cox's proportional-hazard models where WC was included as restricted cubic splines (3 knots). Reference points are the mean WC. Years since the examination in 1999–02 was used as time axis. Adjustments: years between examinations, age in 1999–02, chronic diseases, smoking habits, Mediterranean diet score, energy intake, education, drinking pattern, sports activity. WC in 1993–97: Test of linearity P = 0.05 (linear). Test of effect P<0.0001 (with adjustment for covariates, but without adjustment for body mass index). WC in 1993–97: Test of linearity P = 0.08 (linear). Test of effect P<0.0001 (with adjustment for covariates and body mass index).