Figure_7.tif (2.18 MB)
HPLC-ESI-MS analysis of the fermentation culture of Sa. erythraea EX103.
figure
posted on 2014-09-24, 02:57 authored by Dandan Chen, Junyin Feng, Lei Huang, Qinglin Zhang, Jiequn Wu, Xiangcheng Zhu, Yanwen Duan, Zhinan XuTotal ion current chromatogram (i), and reconstructed base peak chromatograms for 6-deoxy-Er-A (ii), Er-A (iii), 6-deoxy-Er-B (iv), Er-B (v), 6-deoxy-Er-C (vi), Er-C (vii), 6-deoxy-Er-D (viii), and Er-D (ix) are recorded. Note that 6-deoxy-Er-A and Er-B, as well as 6-deoxy-Er-C and Er-D share the same molecular weights and similar polarities, their base peaks are thus overlapping.
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Salt Field ErythromycinsBaicheng salt fieldNRRLmacrolide antibioticsgene complementationdraft genome sequenceGenomic CharacterizationEr biosynthetic gene cluster encodingEH formationEr gene cluster shareserythraea YIM 90600Saccharopolyspora erythraeahalophile Acactivity assaycytochrome P 450 oxidase EryFAcNew Erythromycin Biosynthetic Gene Clusterbiosynthetic pathwaysEr metabolitesnovel Er metaboliteshalophilic actinomyceteerythronolide H
