Glucose and fructose consumption by 3T3-L1 adipocytes exposed to a medium with varying concentrations of glucose, fructose or a combination of both.
Each dot represents the mean ± sem of three different wells. Glucose or hexose consumption are expressed in pmol per cell and day. There were statistically significant (two-way anova) differences (P<0.05) for 11 mM and 22 mM glucose absorption data on day 1 vs. days 2 and 3 (the latter only for 22 mM glucose). There were significant differences for fructose vs. glucose consumption for concentrations higher than 5.5 mM and for days 1 to 3. Fructose consumption in the presence of glucose was also statistically different from that of glucose in the presence of fructose for 2.75 mM to 5.5 mM initial medium levels. In the graphs where glucose + fructose were present in the medium, the X-axis legend shows the hexose measured, and the other present but not shown in the graph is represented between brackets.