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Genomic distribution of methylated and unmethylated CGI.

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posted on 15.02.2012, 14:45 by Satish Sati, Vinay Singh Tanwar, K. Anand Kumar, Ashok Patowary, Vaibhav Jain, Sourav Ghosh, Shadab Ahmad, Meghna Singh, S. Umakar Reddy, Giriraj Ratan Chandak, Manchala Raghunath, Sridhar Sivasubbu, Kausik Chakraborty, Vinod Scaria, Shantanu Sengupta

CpG Island of each methylated and unmethylated Islands were classified in different bins on the basis of size. A – Number of methylated CpG Islands in a particular bin was calculated in different regions like intron, exon, promoter (5 kb upstream from the transcription start site) and rest was put in others category. The count was then normalized by the total number of CpG Island in that bin. B – Number of unmethylated CpG Island of bin was calculated in different regions like intron, exon, promoter (5 kb upstream from the transcription start site) and others, and the count was then normalized by the total number of CpG Islands in that bin.

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