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Genomewide increase in promoter nucleosome occupancy upon activation of human CD4+ T cells.

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posted on 11.08.2011 by Chuong D. Pham, Hillel I. Sims, Trevor K. Archer, Gavin R. Schnitzler

Sequence reads from fifty Solexa lanes for resting versus activated human CD4+ T cells [5] were mapped to the human genome, and relative nucleosome frequency versus TSSes determined for genes at least 2-fold induced or at least 2-fold repressed by activation (A), or for genes whose expression changed less than 1.5-fold as a result of activation (B).

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