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Genome browser displaying the resulting target sites with other genomic features.

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posted on 2013-02-20, 07:45 authored by Jittima Piriyapongsa, Chaiwat Bootchai, Chumpol Ngamphiw, Sissades Tongsima

The position of target site is presented in an integrated view along with other supporting information and genomic annotations on a local genome broswer. The region-level view shows the distribution of putative target sites located within a specified genomic region. Users can highlight (yellow color) to zoom in the interested location for the detail-level view. The target site is displayed in gold box with green line. The conservation score of each nucleotide position (blue color on the bottom) is displayed in the range from 0 to 1. AGO binding-site cluster is represented as distribution of read numbers along the cluster (green color). In this particular case, the presence of miRNA (red color) on the same locus as its binding site represents the cis-regulatory role of miRNA.

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