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Gene expression in M. leprae and BCG infected THP-1 cells.

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posted on 14.06.2013 by Luana Tatiana Albuquerque Guerreiro, Anna Beatriz Robottom-Ferreira, Marcelo Ribeiro-Alves, Thiago Gomes Toledo-Pinto, Tiana Rosa Brito, Patrícia Sammarco Rosa, Felipe Galvan Sandoval, Márcia Rodrigues Jardim, Sérgio Gomes Antunes, Edward J. Shannon, Euzenir Nunes Sarno, Maria Cristina Vidal Pessolani, Diana Lynn Williams, Milton Ozório Moraes

THP-1 cells were infected with BCG Moreau (gray columns) or M. leprae (black columns) at a MOI 2∶1 for 24 hours (n = 6) or uninfected (control, white columns). Among the 47-gene set only genes that showed at least a suggestive result (n = 9) are presented. Two-tailed levels of significance less than or equal to 0.01 (**), 0.05 (*) and 0.1 (.) were considered as “highly significant”, “significant”, and “suggestive”, respectively.