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Gene and polypeptide structures of AgAQP1A and B.

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posted on 16.09.2013, 02:04 by Hitoshi Tsujimoto, Kun Liu, Paul J. Linser, Peter Agre, Jason L. Rasgon

A, genetic structures of the splice variants AgAQP1A and AgAQP1B on Chromosome 3R. The structures are identical from 5’ end to the 4th intron. AgAQP1A consists of 5 exons while AgAQP1B consists of 6 exons. Untranslated regions (UTRs) are shown in red. B, amino-acid sequence alignment by ClustalW2 of the two variants. Predicted transmembrane domains are boxed, while NPA motifs are shaded with grey. Divergent residues at C termini are in white letters in black background. Arrowheads indicate conserved R/ar residues (F53, H177 and R192). * indicates identical residue : indicates similar residue.


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