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GRFT and SVN bind to HCV E2 glycoprotein.

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posted on 21.05.2013, 01:30 by Yutaka Takebe, Carrie J. Saucedo, Garry Lund, Rie Uenishi, Saiki Hase, Takayo Tsuchiura, Norman Kneteman, Koreen Ramessar, D. Lorne J. Tyrrell, Masayuki Shirakura, Takaji Wakita, James B. McMahon, Barry R. O'Keefe

Recombinant glycosylated HCV envelope glycoprotein E2 (strain H77 1a) was bound to 96-well plates and exposed to varying concentrations of both SVN and GRFT. The presence of SVN (A) and GRFT (B) was visualized using rabbit polyclonal anti-GRFT or anti-SVN antibodies as described in the Materials and Methods section. Data points represent the mean of three experiments ± SD.