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Foxp3 expression pre- and post-vaccination.

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posted on 01.09.2010, 00:52 by Mayu O. Frank, Julia Kaufman, Suyan Tian, Mayte Suárez-Fariñas, Salina Parveen, Nathalie E. Blachère, Michael J. Morris, Susan Slovin, Howard I. Scher, Matthew L. Albert, Robert B. Darnell

a. FACS profile of Foxp3 expression in pre- and post-vaccinated peripheral blood gated on CD4+ T cells. A representative patient (#13) is shown. b. Box plots of the percent Foxp3+ cells (gated on CD4+ T cells) pre and post-vaccination in 15 representative patients, including those across the whole range of proliferative responses and changes in PSA slope. The median is shown by the +. Outliers are indicated by •. No difference in pre-vaccine vs. post-vaccine T cell expression of Foxp3 (p = 0.924) was observed.

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