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Flow diagram showing the number of patients who met the inclusion and exclusion criteria in each arm.

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posted on 19.08.2015, 02:52 by Shadi Rashtak, Shahryar Khaleghi, Eric V. Marietta, Mark R. Pittelkow, Joseph J. Larson, Brian D. Lahr, Joseph A. Murray

In the left arm isotretinoin exposure was assessed among diagnosed CD patients and their age- and gender-matched controls (case-control design). In the right arm, latent CD (defined as positive CD serology) was assessed among patients with and without isotretinoin exposure (cohort design).