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Fitting TNNP model to itself.

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posted on 2014-09-24, 03:16 authored by Jaspreet Kaur, Anders Nygren, Edward J. Vigmond

The red dashed curve shows the single cell AP for TNNP model as published [22]. the blue dashed-dotted curve shows the single cell AP waveform generated by genetic algorithm after fitiing AP+Rm. Membrane resistance was evaluated and fitted at three different voltage points as indicated by the markers.

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Fitting Membrane Resistance along with Action Potential Shape in Cardiac Myocytes Improves Convergence: Application of a Multi-Objective Parallel Genetic Algorithm
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rmmseAP morphology datatissue level behaviorrabbit action potentialsparameter setsmodel

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