Expression of senescence-associated genes in primary AFCs and AFiPSCs.
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Heatmap depicting significantly differentially expressed senescence-associated genes in the union of AFiPSCs at approximately passage 20 compared to primary AFCs at passage 17 (AFC P17) (cut off: fold change ≥1.5 or ≤0.667 and FDR-adjusted P-Values for differential expression <0.05). The heatmap is colored by LOG2 average expression signals according to the color key on the bottom. Genes and samples were clustered by similar expression patterns using Eucledian distance measure.