Expression of cellular markers of CH in normotensive- and pre-hypertensive Milan rats.
figure
posted on 2014-04-21, 11:38 authored by Sergej Popov, Hiroshi Takemori, Takeshi Tokudome, Yuanjie Mao, Kentaro Otani, Naoki Mochizuki, Nuno Pires, Maria João Pinho, Anders Franco-Cereceda, Lucia Torielli, Mara Ferrandi, Anders Hamsten, Patricio Soares-da-Silva, Per Eriksson, Alejandro M. Bertorello, Laura Brion<p>Studies were performed in normotensive (MNS) and pre-hypertensive (MHS-pre) Milan rats at 30 days of age. Each bar represents the mean ± s.e.m., n = 6 animals in each group. <b>A)</b> Body weight; <b>B)</b> Left ventricular (LV) weight/body weight (BW) ratio; <b>C)</b> Systolic blood pressure (SBP); <b>D)</b> Brain natriuretic peptide (NPPB) mRNA expression levels; <b>E)</b> β-myosin heavy chain (β-MHC) mRNA expression levels; <b>F)</b> α-myosin heavy chain (α-MHC) mRNA expression levels; <b>G)</b> Representative hematoxylin and eosin stained cross-sections from the left ventricle MNS and MHS-pre rats. Bar: 50 µm; <b>H)</b> Expression levels of mRNA for SIK isoforms.</p>
