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Download fileExpression of DNA damage signaling genes in P2 SMA skeletal muscle is not increased significantly.
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posted on 2014-03-25, 04:12 authored by Saniya Fayzullina, Lee J. MartinA commercially available gene array was used to assay skeletal (back) muscle from SMA mice and control littermates (n = 3). There were no statistically significant changes in the expression of 84 genes (see Table S1 for a complete list of genes). Each circle represents a single gene assayed. The black line denotes a fold-change of 1. Red lines denote a fold-change of 3.
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anatomybiological tissueMuscle tissueMuscle cellsMusculoskeletal systemmusclesnervous systemMotor systemcell biologyCell processesCell deathCellular typesMolecular cell biologygeneticsGenetic dominanceAutosomal recessive diseasesSpinal muscular atrophyAutosomal recessive traitsHuman geneticsneuroscienceDiagnostic medicineneurologyNeurodegenerative diseasesMotor neuron diseasesNeurobiology of disease and regenerationPathology and laboratory medicineanatomical pathologyneuropathologyModel organismsAnimal modelsMouse modelsdnagenesp2smaskeletal