Electromechanical properties of the baseline, isolated RA single cell under control (dark) and AFER (dashed) conditions.
(A) Action potential. (B) Cytosolic Ca2+ concentration. (Inset) Comparison of our simulation results (grey bars) with experimental data (symbols) on APD90 [10–12,14,87,88] and cytosolic Ca2+ reduction [88,90,91]. (C) Sarcomere length shortening and (D) Active force normalised to maximum of Control.