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Effects of sitostanol and cholesterol on NK cells, NKT cells and CD107a expression after exposure to K562 cells.

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posted on 2013-02-19, 21:37 authored by Florence Brüll, Ronald P. Mensink, Mandy F. Steinbusch, Constanze Husche, Dieter Lütjohann, Geert-Jan Wesseling, Jogchum Plat

Sitostanol significantly reduced the percentage of NK cells in asthma patients as well as in healthy controls (p<0.05). Cholesterol lowered the activity of NK cells in asthma patients (p<0.05) and sitostanol did not increase the activity of NKT cells in asthma patients, but only in healthy controls (p<0.05). a = p<0.05 v cyclodextrin; b = p<0.10 v cholesterol; c = p<0.05 v sitostanol; d = p<0.10 v asthma patients.

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