Effects of repeated METH and PCP on the locomotor activity in GluRε1−/− and GluRε4−/− mice.
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Changes in response to repeated administration of (A) METH (1 mg/kg) or (B) PCP (3 mg/kg) (n = 15–25). *p<0.05, **p<0.01, ***p<0.001, compared with Session 1 of the same genotype (paired t-test). Each point represents total locomotor activity (mean ± SEM) during the 60 min period after METH or PCP injection.