Effects of BSE-CD treatment on the NF-κB pathway activation in the liver tissue of mice infected with S. japonicum.
figureposted on 2014-06-18, 03:23 authored by Miao Liu, Qingsi Wu, Peng Chen, Berthold Büchele, Maohong Bian, Shengjian Dong, Dake Huang, Cuiping Ren, Yuxia Zhang, Xin Hou, Thomas Simmet, Jijia Shen
Mice were treated as described in Fig. 1. (A) Sections of the liver tissue were analyzed immunohistochemically for the phosphorylated form of IKK. (B) The activation of NF-κB was measured by EMSA. All data are expressed as mean ± SEM (n = 8 for each group). *P<0.05 versus corresponding infected mice or the cyclodextrin (280 mg/kg) group.
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anatomyhistologycell biologySignal transductioncell signalingSignaling cascadesMolecular cell biologyClinical medicineGastroenterology and hepatologyInfectious diseasesParasitic diseasesHelminth infectionsschistosomiasispharmacologyDrug research and developmentPublic and occupational healthGlobal healthTropical diseasesneglected tropical diseasesHistochemistry and cytochemistry techniquesImmunohistochemistry techniquesImmunohistochemical analysisModel organismsAnimal modelsMouse modelsbse-cdpathwayactivationmiceinfected