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Effects of 1-methoxyoctadecan-1-ol on calpain activation, STEP cleavage and p38 MAPK phosphorylation.

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posted on 08.01.2014, 03:56 by Ji Yeon Jang, Young Whan Choi, Ha Neui Kim, Yu Ri Kim, Jin Woo Hong, Dong Won Bae, Se Jin Park, Hwa Kyoung Shin, Byung Tae Choi

The significant calpain1 activation (A), STEP cleavage (B) and p38 MAPK phosphorylation (C) were shown in the ipsilateral (Ipsil) cerebral hemisphere of photothrombotic ischemic mice compared with the contralateral (Con). **P<0.01, ***P<0.001, vs. vehicle group, Data are expressed as mean±SEM of three separate experiments.